3,3'-Diethyloxacarbocyanine iodide
Names
[ CAS No. ]:
905-96-4
[ Name ]:
3,3'-Diethyloxacarbocyanine iodide
[Synonym ]:
G 1745
MFCD00011952
DOC Iodide
(2Z)-3-ethyl-2-[(E)-3-(3-ethyl-1,3-benzoxazol-3-ium-2-yl)prop-2-enylidene]-1,3-benzoxazole,iodide
3,3'-dietyl oxacarbocyanine iodide
EINECS 212-996-6
Biological Activity
[Description]:
[Related Catalog]:
[References]
Chemical & Physical Properties
[ Melting Point ]:
278ºC (dec.)(lit.)
[ Molecular Formula ]:
C21H21IN2O2
[ Molecular Weight ]:
460.31
[ Exact Mass ]:
460.06500
[ PSA ]:
35.09000
[ LogP ]:
1.08680
MSDS
Safety Information
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xi: Irritant;
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
26-36
[ RIDADR ]:
NONH for all modes of transport
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Articles
J. Immunol. 194(4) , 1983-95, (2015)
Intestinal mucositis represents the most common complication of intensive chemotherapy, which has a severe adverse impact on quality of life of cancer patients. However, the precise pathophysiology re...
Multidrug resistance protein 1 reduces the aggregation of mutant huntingtin in neuronal cells derived from the Huntington's disease R6/2 model.Sci. Rep. 5 , 16887, (2015)
Mutant huntingtin (mHtt) aggregation in the nucleus is the most readily apparent phenotype and cause of neuronal death in Huntington's disease (HD). Inhibiting mHtt aggregation reduces cell death in t...
Structure-activity relationship of cyanine tau aggregation inhibitors.J. Med. Chem. 52 , 3539-47, (2009)
A structure-activity relationship for symmetrical cyanine inhibitors of human tau aggregation was elaborated using a filter trap assay. Antagonist activity depended on cyanine heterocycle, polymethine...