3,3'-Diethylthiacarbocyanine iodide

Names

[ CAS No. ]:
905-97-5

[ Name ]:
3,3'-Diethylthiacarbocyanine iodide

[Synonym ]:
3,3'-diethylthiacarbocyanine iodide
MFCD00011956

Biological Activity

[Description]:

3,3-Diethylthiacarbocyanine iodide is a cyanine dye. 3,3-Diethylthiacarbocyanine iodide can be used in photochemical methods[1][2].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. NK Petrov, et al. The effect of cucurbit[7]uril on photophysical properties of aqueous solution of 3,3′-diethylthiacarbocyanine iodide dye. Chemical Physics Letters. 2009, 96-99.

[2]. M Y. Anikovsky, et al. Complex formation between 3;3´-diethylthiacarbocyanine iodide and DNA and its investigation in aqueous solution. International Journal of Photoenergy. 1999.

Chemical & Physical Properties

[ Melting Point ]:
268-270ºC (dec.)(lit.)

[ Molecular Formula ]:
C₂₁H₂₁IN₂S₂

[ Molecular Weight ]:
492.43900

[ Exact Mass ]:
492.01900

[ PSA ]:
65.29000

[ LogP ]:
2.02380

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DL7061500

CHEMICAL NAME :: Benzothiazolium, 3-ethyl-2-(3-(3-ethyl-2-benzothiazolinylidene)-1-prop enyl)-, iodide

CAS REGISTRY NUMBER :: 905-97-5

LAST UPDATED :: 199007

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C21-H21-N2-S2.I

MOLECULAR WEIGHT :: 492.46

WISWESSER LINE NOTATION :: T56 BNYSJ B2 CU2U1- CT56 BK DSJ B2 &I

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 3 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 10,897,1967

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
26-36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
DL7061500

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Articles

Structure-activity relationship of cyanine tau aggregation inhibitors.

J. Med. Chem. 52 , 3539-47, (2009)

A structure-activity relationship for symmetrical cyanine inhibitors of human tau aggregation was elaborated using a filter trap assay. Antagonist activity depended on cyanine heterocycle, polymethine...

In silico activity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen.

Proc. Natl. Acad. Sci. U. S. A. 105 , 9059-64, (2008)

The growing resistance to current first-line antimalarial drugs represents a major health challenge. To facilitate the discovery of new antimalarials, we have implemented an efficient and robust high-...

Three-dimensional fluorescence lifetime tomography.

Med. Phys. 32(4) , 992-1000, (2005)

Near-infrared fluorescence tomography using molecularly targeted lifetime-sensitive, fluorescent contrast agents have applications for early-stage cancer diagnostics. Yet, although the measurement of ...