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Decoglurant

Names

[ CAS No. ]:
911115-16-7

[ Name ]:
Decoglurant

[Synonym ]:
Decoglurant
UNII-5VX4P0JKC5

Biological Activity

[Description]:

Decoglurant (RO4995819) is a negative allosteric modulator of mGluR2 and mGluR3. Decoglurant is developed as an antidepressant[1].

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> mGluR
Research Areas >> Neurological Disease

[Target]

mGluR2

mGluR3


[References]

[1]. Wilkinson ST, et al. A new generation of antidepressants: an update on the pharmaceutical pipeline for novel and rapid-acting therapeutics in mood disorders based on glutamate/GABA neurotransmitter systems. Drug Discov Today. 2019 Feb;24(2):606-615.

Chemical & Physical Properties

[ Molecular Formula ]:
C21H11F6N5

[ Molecular Weight ]:
447.33600

[ Exact Mass ]:
447.09200

[ PSA ]:
69.83000

[ LogP ]:
4.74100

Related Compounds