Cazpaullone

Names

[ Name ]:
Cazpaullone

[Synonym ]:
CAZPAULLONE
Cazpaullone

Biological Activity

[Description]:

Cazpaullone is a glycogen synthase kinase-3 (GSK-3) inhibitor. Cazpaullone can activate pancreatic beta cell protection and replication. Cazpaullone can be used for the research of diabetes[1].

[Related Catalog]:

Signaling Pathways >> Stem Cell/Wnt >> GSK-3

Research Areas >> Metabolic Disease

Signaling Pathways >> PI3K/Akt/mTOR >> GSK-3

[References]

[1]. Stukenbrock H, et al. 9-cyano-1-azapaullone (cazpaullone), a glycogen synthase kinase-3 (GSK-3) inhibitor activating pancreatic beta cell protection and replication. J Med Chem. 2008 Apr 10;51(7):2196-207.

Chemical & Physical Properties

[ Density]:
1.49±0.1 g/cm3 (20 °C, 760 mmHg)

[ Boiling Point ]:
680.7±50.0 °C (760 mmHg)

[ Molecular Formula ]:
C₁₆H₁₀N₄O

[ Molecular Weight ]:
274.27700

[ Exact Mass ]:
274.08500

[ PSA ]:
81.57000

[ LogP ]:
2.73418

Cazpaullone

Names

Biological Activity

Chemical & Physical Properties

Related Compounds