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Irloxacin

Names

[ CAS No. ]:
91524-15-1

[ Name ]:
Irloxacin

[Synonym ]:
Irloxacin
1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1H-pyrrol-1-yl)-3-quinolinecarboxylic acid
Pirfloxacin
Irloxacinum [Latin]
Irloxacino [Spanish]
pirflossacina
1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-pyrrolyl)-3-quinolinecarboxylic acid
6-fluoro-7-(1-pyrrolyl)-1-ethyl-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid
Irloxacine [French]
E-3432

Biological Activity

[Description]:

Irloxacin (Pirfloxacin) is a quinolone antibacterial agent. Irloxacin shows greater activity with an acid pH. Irloxacin has a good in vitro antimicrobial spectrum against both gram-positive and gram-negative bacteria. Orally active[1].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Anti-infection >> Bacterial

[References]

[1]. Casal M, et al. Preliminary study of the in vitro activity of irloxacin against mycobacteria. Chemotherapy. 1995;41(3):204-207.

[2]. Guzmán A, et al. Acute and subchronic toxicity studies of the new quinolone antibacterial agent irloxacin in rodents. Arzneimittelforschung. 1999;49(5):448-456.

Chemical & Physical Properties

[ Density]:
1.36g/cm3

[ Boiling Point ]:
495.9ºC at 760mmHg

[ Molecular Formula ]:
C16H13FN2O3

[ Molecular Weight ]:
300.28400

[ Flash Point ]:
253.7ºC

[ Exact Mass ]:
300.09100

[ PSA ]:
64.23000

[ LogP ]:
2.64940

[ Index of Refraction ]:
1.634

[ Storage condition ]:
-20°C

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds