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ADX-102

Names

[ CAS No. ]:
916056-79-6

[ Name ]:
ADX-102

Biological Activity

[Description]:

Reproxalap (ADX-102) is a reactive aldehyde species (RASP) sequestering agent for the treatment of dry eye. Reproxalap (ADX-102) covalently binds aldehydes including malondialdehyde and 4-hydroxynonenal[1][2].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Inflammation/Immunology

[References]

[1]. Susan Macdonald, et al. ADX-102, a novel aldehyde trap, reduces nociceptive behavior in mouse models of carrageenan and CFA induced pain.

[2]. Reproxalap Phase 2b Dry Eye Disease Results.

Chemical & Physical Properties

[ Molecular Formula ]:
C12H13ClN2O

[ Molecular Weight ]:
236.70


Related Compounds