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Ansofaxine

Names

[ CAS No. ]:
916918-80-4

[ Name ]:
Ansofaxine

[Synonym ]:
4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenyl 4-methylbenzoate
Benzoic acid, 4-methyl-, 4-[2-(dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenyl ester

Biological Activity

[Description]:

Ansofaxine is a serotonin-norepinephrine reuptake inhibitor (SNRI) used for the research of depression[1].

[Related Catalog]:

Research Areas >> Neurological Disease
Signaling Pathways >> Neuronal Signaling >> Serotonin Transporter

[References]

[1]. Mi W, Yang F, Li H, Xu X, Li L, Tan Q, Wang G, Zhang K, Tian F, Luo J, Xia J, Yuan K, Lu L, Deng J, Tian J, Zhang H. Efficacy, Safety, and Tolerability of Ansofaxine (LY03005) Extended-Release Tablet for Major Depressive Disorder: A Randomized, Double-Blind, Placebo-Controlled, Dose-Finding, Phase 2 Clinical Trial. Int J Neuropsychopharmacol. 2021 Nov 8:pyab074.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
526.4±45.0 °C at 760 mmHg

[ Molecular Formula ]:
C24H31NO3

[ Molecular Weight ]:
381.51

[ Flash Point ]:
272.1±28.7 °C

[ Exact Mass ]:
381.230408

[ LogP ]:
4.83

[ Vapour Pressure ]:
0.0±1.5 mmHg at 25°C

[ Index of Refraction ]:
1.581

Related Compounds