2-Ethacrolein
Names
[ CAS No. ]:
922-63-4
[ Name ]:
2-Ethacrolein
[Synonym ]:
MFCD00010129
Butanal, 2-methylene-
2-Ethacrolein
2-Ethylacrolein
EINECS 213-079-3
α-ethylacrolein
2-Methylenebutanal
2-methylidenebutanal
Chemical & Physical Properties
[ Density]:
0.8±0.1 g/cm3
[ Boiling Point ]:
92.5±0.0 °C at 760 mmHg
[ Melting Point ]:
-101.15°C (estimate)
[ Molecular Formula ]:
C5H8O
[ Molecular Weight ]:
84.116
[ Flash Point ]:
1.1±0.0 °C
[ Exact Mass ]:
84.057518
[ PSA ]:
17.07000
[ LogP ]:
1.07
[ Vapour Pressure ]:
51.5±0.1 mmHg at 25°C
[ Index of Refraction ]:
1.399
[ Storage condition ]:
2-8°C
[ Water Solubility ]:
Soluble in alcohol. Insoluble in water.
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- ES3480000
- CHEMICAL NAME :
- Butyraldehyde, 2-methylene-
- CAS REGISTRY NUMBER :
- 922-63-4
- BEILSTEIN REFERENCE NO. :
- 1098378
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C5-H8-O
- MOLECULAR WEIGHT :
- 84.13
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 289 ppm/4H
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TCLo - Lowest published toxic concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 48400 ppb/6H/13W-I
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - changes in lung weight Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Related to Chronic Data - changes in ovarian weight
MUTATION DATA
- TYPE OF TEST :
- Mutation in microorganisms
- TEST SYSTEM :
- Bacteria - Salmonella typhimurium
- DOSE/DURATION :
- 1 umol/plate
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 264,193,1991
Safety Information
[ Symbol ]:
GHS02, GHS06
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H225-H302 + H312-H330
[ Precautionary Statements ]:
P210-P260-P280-P284-P310
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
F:Flammable;Xn:Harmful;
[ Risk Phrases ]:
R11;R20/21/22
[ Safety Phrases ]:
S16-S26-S28-S36/37/39
[ RIDADR ]:
UN 3384
[ RTECS ]:
ES3480000
[ Packaging Group ]:
II
[ HS Code ]:
2912190090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2912190090
[ Summary ]:
2912190090 acyclic aldehydes without other oxygen function。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%
Articles
J. Am. Chem. Soc. 124(17) , 4628-41, (2002)
Described is a concise, highly stereocontrolled strategy to the Aspidosperma family of indole alkaloids, one that is readily adapted to the asymmetric synthesis of these compounds. The strategy is dem...
Immunological response from an entirely carbohydrate antigen: design of synthetic vaccines based on Tn-PS A1 conjugates.J. Am. Chem. Soc. 131(28) , 9622-3, (2009)
An entirely carbohydrate-based immunogen consisting of a zwitterionic polysaccharide (ZPS) PS A1 and the well-known tumor antigen Tn has been designed, synthesized, and studied for immunological effec...
Mutagenicity of 2-methylacrolein, 2-ethylacrolein and 2-propylacrolein in Salmonella typhimurium TA100. A comparative study.Mutat. Res. 264(4) , 193-6, (1991)
The C2-alkylated acrolein derivatives 2-methylacrolein, 2-ethylacrolein and 2-propylacrolein are mutagenic in Salmonella typhimurium TA100. They are direct mutagens, their mutagenic potency being inve...