5-hydroxy Omeprazole

Names

[ Name ]:
5-hydroxy Omeprazole

[Synonym ]:
Hydroxyomeprazole
4-Methoxy-6-[[(5-Methoxy-1H-benziMidazol-2-yl)sulfinyl]Methyl]-5-Methyl-3-pyridineMethanol SodiuM Salt
4-Methoxy-6-[[(5-methoxy-1H-benzimidazol-2-yl)sulfinyl]methyl]-5-methyl-3-pyridinemethanol
2-[(5-HYDROXYMETYL-4-METHOXY-3-METHYL-PYRIDIN-2-YL)-METHYLSULFO]-BENZIMIDAZOLE
5-Hydroxy Omeprazole Sodium Salt
HydroxyoMeprazole SodiuM Salt
[4-Methoxy-6-[(6-methoxy-1H-benzimidazol-2-yl)sulfinylmethyl]-5-methylpyridin-3-yl]methanol
5-hydroxymethylomeprazole

Biological Activity

[Description]:

5-Hydroxyomeprazole is the major metabolite of Omeprazole (HY-B0113).

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

Chemical & Physical Properties

[ Density]:
1.45g/cm3

[ Boiling Point ]:
656.3ºC at 760mmHg

[ Melting Point ]:
144-146ºC

[ Molecular Formula ]:
C₁₇H₁₉N₃O₄S

[ Molecular Weight ]:
361.41500

[ Flash Point ]:
350.7ºC

[ Exact Mass ]:
361.11000

[ PSA ]:
116.54000

[ LogP ]:
2.94930

[ Index of Refraction ]:
1.692

[ Storage condition ]:
-20°C Freezer, Under Inert Atmosphere

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
26-36

[ RIDADR ]:
NONH for all modes of transport

Articles

Development of an in vitro cytochrome P450 cocktail inhibition assay for assessing the inhibition risk of drugs of abuse.

Toxicol. Lett. 230(1) , 28-35, (2014)

Drugs of abuse are not tested for cytochrome P450 (CYP) inhibition potential before distribution. Therefore, a cocktail assay should be developed for testing the inhibition potential for all relevant ...

In vitro cytochrome P450 inhibition potential of methylenedioxy-derived designer drugs studied with a two-cocktail approach.

Arch. Toxicol. 90 , 305-18, (2016)

In vitro cytochrome P450 (CYP) inhibition assays are common approaches for testing the inhibition potential of drugs for predicting potential interactions. In contrast to marketed medicaments, drugs o...

Cytochrome P450 inhibition potential of new psychoactive substances of the tryptamine class.

Toxicol. Lett. 241 , 82-94, (2015)

New psychoactive substances (NPS) are not tested for their cytochrome P450 (CYP) inhibition potential before consumption. Therefore, this potential was explored for tryptamine-derived NPS (TDNPS) incl...