Cerlapirdine

Names

[ Name ]:
Cerlapirdine

[Synonym ]:
SAM-531
UNII-EK40PJ0V49
Cerlapirdine

Biological Activity

[Description]:

Cerlapirdine (SAM-531, PF-05212365) is a selective and potent full antagonist of the 5-hydroxytryptamine 6 (5-HT6) receptor. Cerlapirdine has the potential for researching the Alzheimer's disease[1].

[Related Catalog]:

Research Areas >> Neurological Disease

Signaling Pathways >> GPCR/G Protein >> 5-HT Receptor

Signaling Pathways >> Neuronal Signaling >> 5-HT Receptor

[Target]

5-HT6 Receptor

[References]

[1]. Tse S, et al. Disposition and metabolic profiling of [(14)C]cerlapirdine using accelerator mass spectrometry. Drug Metab Dispos. 2014;42(12):2023-2032.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₂H₂₃N₃O₃S

[ Molecular Weight ]:
409.50100

[ Exact Mass ]:
409.14600

[ PSA ]:
83.67000

[ LogP ]:
4.96020

Cerlapirdine

Names

Biological Activity

Chemical & Physical Properties

Related Compounds