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Iohexol-d5

Names

[ CAS No. ]:
928623-33-0

[ Name ]:
Iohexol-d5

Biological Activity

[Description]:

Iohexol-d5 is deuterium labeled Iohexol. Iohexol is a radiographic contrast agent and can be applied for myelography, computerized tomography (cisternography, ventriculography) and MicroCT imaging in vivo[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Autophagy >> Autophagy
Signaling Pathways >> Autophagy >> Mitophagy

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

[2]. James F Hainfeld, et al. Small, Long Blood Half-Life Iodine Nanoparticle for Vascular and Tumor Imaging. Sci Rep

Chemical & Physical Properties

[ Molecular Formula ]:
C19H21D5I3N3O9

[ Molecular Weight ]:
826.17

[ Exact Mass ]:
825.91200

[ PSA ]:
206.87000


Related Compounds