Skimmin
Names
[ CAS No. ]:
93-39-0
[ Name ]:
Skimmin
[Synonym ]:
2H-1-Benzopyran-2-one, 7- (β-D-glucopyranosyloxy)-
7-(Glucosyloxy)coumarin
Skimmin
7-Hydroxycoumarin-7-glucoside
Skimmine
UMBELLIFERONE GLUCOSIDE
2H-1-Benzopyran-2-one, 7-(β-D-glucopyranosyloxy)-
Coumarin, 7-(β-D-glucopyranosyloxy)-
2-Oxo-2H-chromen-7-yl β-D-glucopyranoside
HYDROXYCOUMARIN-GLUCOSIDE,7
Skimmin (8CI)
7-(b-D-Glucopyranosyloxy)-2H-1-benzopyran-2-one
Biological Activity
[Description]:
[Related Catalog]:
[References]
Chemical & Physical Properties
[ Density]:
1.6±0.1 g/cm3
[ Boiling Point ]:
632.0±55.0 °C at 760 mmHg
[ Melting Point ]:
221-222ºC
[ Molecular Formula ]:
C15H16O8
[ Molecular Weight ]:
324.28
[ Flash Point ]:
239.3±25.0 °C
[ Exact Mass ]:
324.084503
[ PSA ]:
129.59000
[ LogP ]:
-1.50
[ Vapour Pressure ]:
0.0±1.9 mmHg at 25°C
[ Index of Refraction ]:
1.661
Safety Information
[ Hazard Codes ]:
Xi
[ RIDADR ]:
NONH for all modes of transport
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Articles
Evid. Based. Complement. Alternat. Med. 2013 , 819296, (2013)
Skimmin is one of the major pharmacologically active molecules present in Hydrangea paniculata, a medical herb used in the traditional Chinese medicine as an anti-inflammatory agent. In the current st...
Skimmin, a coumarin, suppresses the streptozotocin-induced diabetic nephropathy in wistar rats.Eur. J. Pharmacol. 692(1-3) , 78-83, (2012)
Skimmin, a major active ingredient from Hydrangea paniculata, was considered to have the possible preventive effect on the progression of diabetic nephropathy based on the traditional Chinese medicine...