(S)-Venlafaxine

Names

[ Name ]:
(S)-Venlafaxine

[Synonym ]:
1-[(1S)-2-(DIMETHYLAMINO)-1-(4-METHOXYPHENYL)ETHYL]CYCLOHEXANOL
(S)-VENLAFAXINE
R(-)-1-[2-(dimethylamino)-1-(4-methoxyphenyl)-ethyl]cyclohexanol
(-)-Venlafaxine
(1R)-1-[2-dimethylamino-1-(4-methoxy-phenyl)-ethyl]cyclohexanol
BIDD:GT0838
R-venlafaxine

Biological Activity

[Description]:

(S)-Venlafaxine is the (S)-configuration of Venlafaxine. Venlafaxine is an orally active, potent serotonin (5-HT)/norepinephrine (NE) reuptake dual inhibitor. Venlafaxine is an antidepressant agent[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Neuronal Signaling >> Serotonin Transporter

[References]

[1]. Bymaster FP, et al. Comparative affinity of duloxetine and venlafaxine for serotonin and norepinephrine transporters in vitro and in vivo, human serotonin receptor subtypes, and other neuronal receptors. Neuropsychopharmacology. 2001 Dec;25(6):871-80.

Chemical & Physical Properties

[ Density]:
1.06g/cm3

[ Boiling Point ]:
397.575ºC at 760 mmHg

[ Melting Point ]:
102-104ºC

[ Molecular Formula ]:
C₁₇H₂₇NO₂

[ Molecular Weight ]:
277.40200

[ Flash Point ]:
194.246ºC

[ Exact Mass ]:
277.20400

[ PSA ]:
32.70000

[ LogP ]:
3.03560

[ Index of Refraction ]:
1.544

(S)-Venlafaxine

Names

Biological Activity

Chemical & Physical Properties

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds