Nilofabicin

Names

[ Name ]:
Nilofabicin

[Synonym ]:
unii-4x6t64d64x

Biological Activity

[Description]:

Nilofabicin is an enoyl-(acyl-carrier protein) reductase (FabI) inhibitor. Nilofabicin had an MIC(90) of 0.5 microg/ml for Staphylococcus aureus strains and was more potent than either linezolid or vancomycin[1].

[Related Catalog]:

Research Areas >> Infection

Research Areas >> Inflammation/Immunology

Signaling Pathways >> Anti-infection >> Bacterial

[References]

[1]. Jong Hwa Yum,et, al. In Vitro Activities of CG400549, a Novel FabI Inhibitor, against Recently Isolated Clinical Staphylococcal Strains in Korea. Antimicrob Agents Chemother. 2007 Jul; 51(7): 2591–2593.

Chemical & Physical Properties

[ Density]:
1.273 g/cm3

[ Boiling Point ]:
607.121ºC at 760 mmHg

[ Molecular Formula ]:
C₁₉H₂₀N₂O₂S

[ Molecular Weight ]:
340.44

[ Flash Point ]:
320.975ºC

[ Exact Mass ]:
340.12500

[ PSA ]:
85.49000

[ LogP ]:
4.05140

[ Storage condition ]:
-20°C

Safety Information

[ HS Code ]:
2934999090

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%