Iodo-PEG4-N3
Names
[ CAS No. ]:
936917-36-1
[ Name ]:
Iodo-PEG4-N3
[Synonym ]:
Ethane, 1-(2-azidoethoxy)-2-[2-(2-iodoethoxy)ethoxy]-
1-Azido-2-{2-[2-(2-iodoethoxy)ethoxy]ethoxy}ethane
Biological Activity
[Description]:
Iodo-PEG4-N3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
[Related Catalog]:
[Target]
PEGs
[In Vitro]
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
[References]
Chemical & Physical Properties
[ Molecular Formula ]:
C8H16IN3O3
[ Molecular Weight ]:
329.135
[ Exact Mass ]:
329.023621
[ LogP ]:
0.81