1-Bromo-4-phenoxybenzene-d5

Names

[ CAS No. ]:
93951-83-8

[ Name ]:
1-Bromo-4-phenoxybenzene-d5

[Synonym ]:
4-Bromophenyl phenyl-d5 ether

Biological Activity

[Description]:

1-Bromo-4-phenoxybenzene-d5 is the deuterium labeled 1-Bromo-4-phenoxybenzene[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

Chemical & Physical Properties

[ Density]:
1.451 g/mL at 25ºC

[ Boiling Point ]:
305ºC(lit.)

[ Molecular Formula ]:
C12H4BrD5O

[ Molecular Weight ]:
254.13400

[ Flash Point ]:
113ºC

[ Exact Mass ]:
253.01500

[ PSA ]:
9.23000

[ LogP ]:
4.24140

Safety Information

[ Symbol ]:

GHS05, GHS07, GHS09

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H302-H317-H318-H410

[ Precautionary Statements ]:
P273-P280-P305 + P351 + P338-P501

[ Hazard Codes ]:
N: Dangerous for the environment;

[ Risk Phrases ]:
50/53

[ Safety Phrases ]:
60-61

[ RIDADR ]:
UN 3082 9/PG 3

Related Compounds