acenaphthylene d8

Names

[ Name ]:
acenaphthylene d8

[Synonym ]:
MFCD00143527
Acenaphthylene-d8

Biological Activity

[Description]:

Acenaphthylene-d8 is the deuterium labeled Acenaphthylene[1]. Acenaphthylene is a polycyclic aromatic hydrocarbon (PAH). PAHs are derived naturally from coal and tar deposits, and produced by incomplete combustion of organic matter[2].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

[2]. Fabienne Reisen, et al. Reactions of hydroxyl radicals and ozone with acenaphthene and acenaphthylene. Environ Sci Technol. 2002 Oct 15;36(20):4302-11.

[3]. Amin Kiani, et al. Monitoring of polycyclic aromatic hydrocarbons and probabilistic health risk assessment in yogurt and butter in Iran. Food Sci Nutr. 2021 Feb 149(4):2114-2128.

Chemical & Physical Properties

[ Density]:
1.249g/cm3

[ Boiling Point ]:
280ºC(lit.)

[ Melting Point ]:
92-95ºC(lit.)

[ Molecular Formula ]:
C₁₂D₈

[ Molecular Weight ]:
160.24100

[ Flash Point ]:
137.2ºC

[ Exact Mass ]:
160.11300

[ LogP ]:
3.32360

[ Index of Refraction ]:
1.731

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
26-36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Articles

Levels of PAHs in the waters, sediments, and shrimps of Estero de Urias, an estuary in Mexico, and their toxicological effects.

ScientificWorldJournal 2012 , 687034, (2012)

PAHs were measured in water, sediment, and shrimps of Estero de Urias, an estuary in Sinaloa, Mexico, during the rainy and dry seasons, and analyzed for eleven PAHs routinely detected in samples. Phen...