4,4'-ddt d8

Names

[ Name ]:
4,4'-ddt d8

[Synonym ]:
2,2-bis-(p-benzyloxyphenyl)propane
Benzene,1,1'-(1-methylethylidene)bis[4-(phenylmethoxy)
2,2-bis(p-chlorotetradeuteriophenyl)-1,1,1-trichloroethane

Biological Activity

[Description]:

Chlorophenothane-d8 is the deuterium labeled Chlorophenothane. Chlorophenothane has stomach poisoning and contact killing effects. Chlorophenothane has been widely used as an insecticide[1][2].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₄HCl₅D₈

[ Molecular Weight ]:
362.53600

[ Exact Mass ]:
359.96500

[ LogP ]:
6.49550

[ Storage condition ]:
?20°C

MSDS

Click to get detail MSDS

Safety Information

[ Hazard Codes ]:
T: Toxic;N: Dangerous for the environment;

[ Risk Phrases ]:
25-40-48/25-50/53

[ Safety Phrases ]:
22-36/37-45-60-61

[ RIDADR ]:
UN2811 6.1/PG 3

Articles

Evaluation of follicular synchronization caused by estrogen administration and its reproductive outcome.

PLoS ONE 10 , e0127595, (2015)

To evaluate multiple follicular development synchronization after estrogen stimulation in prepubertal mice, follicular responsiveness to gonadotropin superovulation, the prospective reproductive poten...

Leptin produced by obese adipose stromal/stem cells enhances proliferation and metastasis of estrogen receptor positive breast cancers.

Breast Cancer Res. 17 , 112, (2015)

The steady increase in the incidence of obesity among adults has been paralleled with higher levels of obesity-associated breast cancer. While recent studies have suggested that adipose stromal/stem c...

The immunohistochemical peptidergic expression of leptin is associated with recurrence of malignancy in laryngeal squamous cell carcinoma.

Acta Otorhinolaryngol. Ital. 35 , 15-22, (2015)

Leptin is a peptide that plays a key role in the control of satiety, energy expenditure, food intake and various reproductive processes. In the last years, the expression of leptin had been found in m...