Benzylparaben

Names

[ CAS No. ]:
94-18-8

[ Name ]:
Benzylparaben

[Synonym ]:
Benzyl 4-hydroxybenzoate
BASEPTOL
Benzoic acid, 4-hydroxy-, phenylmethyl ester
MFCD00016471
Benzylparaben
EINECS 202-311-9
PARABEN,BENZYL
4-Hydroxybenzoic acid benzyl ester
Benzoic acid, p-hydroxy-, benzyl ester (8CI)
Benzyl parabe
Parosept
UNII-8Y41DYV4VG
benzyl 4-hydroxy-benzoate
Benzyl Paraben
POB-BZ
benzyl para-hydroxybenzoate
PARABEN,BUTYL
Nipabenzyl
4-HOC6H4CO2Bn
Solbrol Z

Biological Activity

[Description]:

Benzyl 4-hydroxybenzoate is a prominent material. Benzyl 4-hydroxybenzoate can be used as an excipient, such as bacteriostatic agent, preservative. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1][2].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Solanki S S B, et al. Growth and characterization of benzyl 4-hydroxybenzoate single crystal by vertical Bridgman technique for optical applications[J]. Optics & Laser Technology, 2018, 103: 163-169.

[2]. Elder DP, et al. Pharmaceutical excipients - quality, regulatory and biopharmaceutical considerations. Eur J Pharm Sci. 2016 May 25;87:88-99.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
389.8±17.0 °C at 760 mmHg

[ Melting Point ]:
109-112 °C(lit.)

[ Molecular Formula ]:
C₁₄H₁₂O₃

[ Molecular Weight ]:
228.25

[ Flash Point ]:
168.0±13.7 °C

[ Exact Mass ]:
228.078644

[ PSA ]:
46.53000

[ LogP ]:
3.64

[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C

[ Index of Refraction ]:
1.607

[ Storage condition ]:
Refrigerator

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
DH2691000

[ HS Code ]:
2918290000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2918290000

[ Summary ]:
HS: 2918290000 other carboxylic acids with phenol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) VAT:17.0% MFN tariff:6.5% General tariff:30.0%

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