JNJ-38158471
Names
[ CAS No. ]:
951151-97-6
[ Name ]:
JNJ-38158471
[Synonym ]:
1-[4-({6-Amino-5-[(E)-(methoxyimino)methyl]-4-pyrimidinyl}oxy)-2-chlorophenyl]-3-ethylurea
Urea, N-[4-[[6-amino-5-[(E)-(methoxyimino)methyl]-4-pyrimidinyl]oxy]-2-chlorophenyl]-N'-ethyl-
JNJ-38158471
JNJ 38158471
(E)-1-(4-(6-amino-5-((methoxyimino)methyl)pyrimidin-4-yloxy)-2-chlorophenyl)-3-ethylurea
Biological Activity
[Description]:
[Related Catalog]:
[Target]
VEGFR-2:40 nM (IC50)
RET:180 nM (IC50)
c-Kit:500 nM (IC50)
[In Vitro]
[In Vivo]
[References]
Chemical & Physical Properties
[ Density]:
1.4±0.1 g/cm3
[ Molecular Formula ]:
C15H17ClN6O3
[ Molecular Weight ]:
364.787
[ Exact Mass ]:
364.105072
[ PSA ]:
123.75000
[ LogP ]:
4.05
[ Index of Refraction ]:
1.637
Safety Information
[ Hazard Codes ]:
Xi