viFSP1

Names

[ CAS No. ]:
951945-67-8

[ Name ]:
viFSP1

Biological Activity

[Description]:

viFSP1 is a species-independent inhibitor of FSP1 that induces ferroptosis in FSP1-dependent cells. viFSP1 targets the highly conserved NAD(P)H binding pocket of FSP1 and directly inhibits FSP1. viFSP1 induces lipid peroxidation and has anticancer activity[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Apoptosis >> Ferroptosis
Signaling Pathways >> Others >> Others

[Target]

FSP1[1]


[References]

[1]. Nakamura T et al. Integrated chemical and genetic screens unveil FSP1 mechanisms of ferroptosis regulation. Nat Struct Mol Biol. 2023 Nov;30(11):1806-1815.  

Chemical & Physical Properties

[ Molecular Formula ]:
C16H17N3O3S

[ Molecular Weight ]:
331.39

Related Compounds