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hCAII-IN-8

Names

[ CAS No. ]:
952306-80-8

[ Name ]:
hCAII-IN-8

Biological Activity

[Description]:

hCAII-IN-8, an amide, is a highly selective carbonic anhydrase (CA) inhibitor with an IC50 value of 0.18 μM against hCA II[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Metabolic Enzyme/Protease >> Carbonic Anhydrase

[Target]

hCA II:0.18 μM (IC50)


[In Vitro]

hCAII-IN-8 (化合物 9; 100 μM; 24-48 小时) 与对照相比，对 HEK-293 T 细胞没有细胞毒性，细胞活力 >90%[1]。

[References]

[1]. Zahid Hussain, et al. Synthesis and Evaluation of Amide and Thiourea Derivatives as Carbonic Anhydrase (CA) Inhibitors. ACS Omega. 2022 Dec 6;7(50):47251-47264.  

Chemical & Physical Properties

[ Molecular Formula ]:
C15H16N2O5S

[ Molecular Weight ]:
336.36

Related Compounds