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Lucidenic acid B

Names

[ CAS No. ]:
95311-95-8

[ Name ]:
Lucidenic acid B

[Synonym ]:
Lucidenic-acid-B

Biological Activity

[Description]:

Lucidenic acid B is a natural compound isolated from Ganoderma lucidum, induces apoptosis of cancer cells, and causes the activation of caspase-9 and caspase-3, and cleavage of PARP. Lucidenic acid B does not affect the cell cycle profile, or the number of necrotic cells[1].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Apoptosis
Research Areas >> Cancer

[Target]

Apoptosis[1]


[References]

[1]. Hsu CL, et al. Lucidenic acid B induces apoptosis in human leukemia cells via a mitochondria-mediated pathway. J Agric Food Chem. 2008 Jun 11;56(11):3973-80.

Chemical & Physical Properties

[ Melting Point ]:
179-181 °C

[ Molecular Formula ]:
C27H38O7

[ Molecular Weight ]:
474.58600

[ Exact Mass ]:
474.26200

[ PSA ]:
128.97000

[ LogP ]:
3.10530

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds