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zinc,(E,3R,5S)-7-[4-(4-fluorophenyl)-2-[methyl(methylsulfonyl)amino]-6-propan-2-ylpyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid

Names

[ CAS No. ]:
953412-08-3

[ Name ]:
zinc,(E,3R,5S)-7-[4-(4-fluorophenyl)-2-[methyl(methylsulfonyl)amino]-6-propan-2-ylpyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid

[Synonym ]:
UNII-70VE4E19Z7
Rosuvastatin zinc

Biological Activity

[Description]:

Rosuvastatin zinc salt (Rosuvastatin zinc) is a zinc-containing form of Rosuvastatin (HY-17504A). Rosuvastatin is a HMG-CoA reductase inhibitor and can be used for atherosclerosis research[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease
Signaling Pathways >> Others >> Others
Research Areas >> Metabolic Disease

[References]

[1]. Watanabe M, et al. Synthesis and biological activity of methanesulfonamide pyrimidine- and N-methanesulfonyl pyrrole-substituted 3,5-dihydroxy-6-heptenoates, a novel series of HMG-CoA reductase inhibitors. Bioorg Med Chem. 1997 Feb;5(2):437-44.

Chemical & Physical Properties

[ Molecular Formula ]:
C44H56F2N6O12S2Zn

[ Molecular Weight ]:
1028.46000

[ Exact Mass ]:
1026.27000

[ PSA ]:
298.60000

[ LogP ]:
6.96250

Related Compounds