Presenilin 1 (349-361)

Names

[ CAS No. ]:
956004-39-0

[ Name ]:
Presenilin 1 (349-361)

Biological Activity

[Description]:

Presenilin 1 (349-361) is an active petide, and synthetic peptides representing amino acids 349–361 can be phosphorylated by glycogen synthase kinase-3β(GSK3β) in vitro. Presenilin 1 (349-361) can be used for the research of various diseases[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others

[In Vitro]

Presenilin 1 (349-361) reduces the interaction with beta-catenin leading to decreased phosphorylation and ubiquitination of beta-catenin when structural change, thereby increases its nuclear signaling and the transcription of target genes, including c-MYC[1].

Chemical & Physical Properties

[ Molecular Formula ]:
C56H93N21O19

[ Molecular Weight ]:
1364.47

Related Compounds