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5-Ethyl-4-methyl-1H-pyrazole-3-carboxylicacid

Names

[ CAS No. ]:
957129-38-3

[ Name ]:
5-Ethyl-4-methyl-1H-pyrazole-3-carboxylicacid

[Synonym ]:
5-Ethyl-4-methyl-1H-pyrazole-3-carboxylic acid

Biological Activity

[Description]:

GPR109 receptor agonist-2 (Compound 5) is a selective GPR109a agonist with a pEC50 of 5.53[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease
Signaling Pathways >> GPCR/G Protein >> GPR109A

[Target]

pEC50: 5.53 (GPR109a)[1]


[References]

[1]. Skinner PJ, et al. Fluorinated pyrazole acids are agonists of the high affinity niacin receptor GPR109a. Bioorg Med Chem Lett. 2007 Oct 15;17(20):5620-3.  

Chemical & Physical Properties

[ Density]:
1.257±0.06 g/cm3 (20 °C, 760 mmHg)

[ Boiling Point ]:
383.2±30.0 °C (760 mmHg)

[ Molecular Formula ]:
C7H10N2O2

[ Molecular Weight ]:
154.17

[ Exact Mass ]:
154.07400

[ PSA ]:
65.98000

[ LogP ]:
0.97870

[ Storage condition ]:
2-8°C


Related Compounds