Lactobionic acid

Names

[ CAS No. ]:
96-82-2

[ Name ]:
Lactobionic acid

[Synonym ]:
EINECS 202-538-3
D-gluconic acid, 4-O-b-D-galactopyranosyl-
D-Gluconic acid, 4-O-β-D-galactopyranosyl-
LactobionS
LACTOBIONIC ACID(RG)
4-O-β-D-Galactopyranosyl-D-gluconic acid
LaCLobionic Acid
LACTOBIONIC ACID POWDER
LACTOBIONIC ACID FREE ACID
4-O-b-D-galactopyranosyl-D-gluconic acid
4-(b-D-Galactosido)-D-gluconic Acid
MFCD00078147
Lactobionic acid
(2R,3R,4R,5R)-2,3,5,6-Tetrahydroxy-4-{[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}hexanoic acid

Biological Activity

[Description]:

Lactobionic acid is a bionic acid naturally found in the Caspian Sea yogurt and chemically constituted of a gluconic acid bonded to a galactose. Lactobionic acid has antioxidant, antimicrobial, chelating, stabilizer, acidulant, and moisturizing properties[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Bacterial

[References]

[1]. Cardoso T, et al. Lactobionic Acid as a Potential Food Ingredient: Recent Studies and Applications. J Food Sci. 2019 Jul;84(7):1672-1681.

Chemical & Physical Properties

[ Density]:
1.8±0.1 g/cm3

[ Boiling Point ]:
864.7±65.0 °C at 760 mmHg

[ Melting Point ]:
113-118 °C(lit.)

[ Molecular Formula ]:
C₁₂H₂₂O₁₂

[ Molecular Weight ]:
358.296

[ Flash Point ]:
319.1±27.8 °C

[ Exact Mass ]:
358.111115

[ PSA ]:
217.60000

[ LogP ]:
-4.06

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.648

[ Water Solubility ]:
10 g/100 mL

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
1

[ HS Code ]:
2932999099

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2932999099

[ Summary ]:
2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Galactosylated pullulan-curcumin conjugate micelles for site specific anticancer activity to hepatocarcinoma cells.

Colloids Surf. B Biointerfaces 133 , 347-55, (2015)

Galactosylated pullulan-curcumin conjugate (LANH2-Pu Ald-Cur SA) is developed for target specific delivery of curcumin to hepatocarcinoma cells by five step synthetic strategy, which includes oxidatio...

Galactosylated nanostructured lipid carriers for delivery of 5-FU to hepatocellular carcinoma.

J. Liposome Res. 22(3) , 224-36, (2012)

The aim of the present study was to design a targeted delivery system of 5-fluorouracil (5-FU) for hepatocellular carcinoma (HCC). Lactobionic acid (LB) was conjugated to stearyl amine (SA) by a chemi...

Targeting liver cancer via ASGP receptor using 5-FU-loaded surface-modified PLGA nanoparticles.

J. Microencapsul. 31(5) , 479-87, (2014)

Liver cancer is widespread liver malignancy in the world, for an estimated one million deaths annually.In present work, lactobionic acid conjugated PLGA nanoparticles (LDNPs) bearing 5-Fluorouracil (5...