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Palonidipine

Names

[ CAS No. ]:
96515-73-0

[ Name ]:
Palonidipine

Biological Activity

[Description]:

Palonidipine is a calcium antagonist which is potential for the therapy of angina-pectoris and hypertension[1][2][3].

[Related Catalog]:

Signaling Pathways >> Membrane Transporter/Ion Channel >> Calcium Channel
Research Areas >> Cardiovascular Disease

[Target]

Calcium[1]


[References]

[1]. Okamiya Y, et al. [Effect of palonidipine hydrochloride (TC-81), a novel calcium antagonist, on the canine coronary artery]. Nihon Yakurigaku Zasshi. 1993 Jul;102(1):23-33.

[2]. Kishimoto T, et al. [Effect of palonidipine hydrochloride (TC-81), a new dihydropyridine derivative, on various myocardial ischemic models]. Nihon Yakurigaku Zasshi. 1993 Aug;102(2):85-100.

[3]. K. Sunakawa, et al. Effects of palonidipine hydrochloride on respiratory and cardiovascular systems. January 1993

Chemical & Physical Properties

[ Density]:
1.216g/cm3

[ Boiling Point ]:
619.1ºC at 760 mmHg

[ Molecular Formula ]:
C29H34FN3O6

[ Molecular Weight ]:
539.60

[ Flash Point ]:
328.2ºC

[ Exact Mass ]:
539.24300

[ PSA ]:
113.69000

[ LogP ]:
5.69510

[ Index of Refraction ]:
1.562

Related Compounds