(+/-)-2,2'-Bis(diphenylphosphino)-1,1'-binaphthyl

Names

[ Name ]:
(+/-)-2,2'-Bis(diphenylphosphino)-1,1'-binaphthyl

[Synonym ]:
L66J CPR&R& B- BL66J CPR&R
2,2'-Bis(diphenylphosphanyl)-1,1'-binaphthalene
Phosphine, 1,1'-[1,1'-binaphthalene]-2,2'-diylbis[1,1-diphenyl-
rac-2,2'-Bis-(diphenylphosphino)-1,1'-binaphthyl
1,1'-binaphthalene-2,2'-diylbis(diphenylphosphane)
(±)-BINAP
1,1'-Binaphthalen-2,2'-diylbis(diphenylphosphan)
1,1'-Binaphthalene-2,2'-diylbis(diphenylphosphine)
rac-binap
1,1'-[1,1'-Binaphthalene]-2,2'-diylbis[1-phenyl-1-(phenylmethyl)phosphine
DL-2,2'-Bis(diphenylphosphino)-1,1'-dinaphthalene
UNII:OX12238KWH
(r)-(+)-2,2'-bis(diphenylphosphino)-1,1'-binaphthyl
BINAP
Phosphine, 1,1'-[1,1'-binaphthalene]-2,2'-diylbis[1-phenyl-1-(phenylmethyl)-
[1,1'-Binaphthalene]-2,2'-diylbis[diphenylphosphine]
MFCD00010805
UNII:970O8508MB
1,1'-Binaphthalene-2,2'-diylbis[benzyl(phenyl)phosphine]
UNII:4F1X2F8NA3
(+/-)-2,2'-Bis(diphenylphosphino)-1,1'-binaphthyl

Biological Activity

[Description]:

(Rac)-BINAP is the inactive isomer of (R)-BINAP (HY-W017757), and can be used as an experimental control. (R)-BINAP is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Xue CB, et al. Discovery of INCB8761/PF-4136309, a Potent, Selective, and Orally Bioavailable CCR2 Antagonist. ACS Med. Chem. Lett., 2011, 2 (12), pp 913-918.

Chemical & Physical Properties

[ Boiling Point ]:
724.3±55.0 °C at 760 mmHg

[ Melting Point ]:
280-285ºC

[ Molecular Formula ]:
C₄₄H₃₂P₂

[ Molecular Weight ]:
622.67

[ Flash Point ]:
419.0±37.8 °C

[ Exact Mass ]:
622.197937

[ PSA ]:
27.18000

[ LogP ]:
13.38

[ Vapour Pressure ]:
0.0±2.3 mmHg at 25°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Articles

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J. Med. Chem. 49 , 5571, (2006)

A novel class of 3-demethoxy-3-glycosylaminothiocolchicines (7) was prepared and tested for muscle relaxant activity. The syntheses were performed starting from the new 3-amino-3-demethoxythiocolchici...

The preparation of bi-functional organophosphine oxides as potential antitumor agents.

Eur. J. Med. Chem. 45 , 5527-30, (2010)

Following our previously reported pyridinyl phosphine oxides as antitumor agents, we targeted the commercially available C(2)-axial chiral organophosphine ligand catalysts, such as 2,2'-bis(diphenylph...

Organometallics 23 , 3398-3416, (2004)