S(-)-Bisoprolol

Names

[ Name ]:
S(-)-Bisoprolol

[Synonym ]:
(-)-Bisoprolol
(S)-bis(4-chlorophenyl)(pyrrolidin-2-yl)methanol
(R)-Bis(4-chlorophenyl)(pyrrolidin-2-yl)methanol
(S)-bisoprolol

Biological Activity

[Description]:

S(-)-Bisoprolol is a S(-)-enantiomer of Bisoprolol. Bisoprolol is a potent, selective and orally active β1-adrenergic receptor blocker. Bisoprolol has little activity on β2-receptor and has the potential for hypertension, coronary artery disease and stable ventricular dysfunction research[1][2].

[Related Catalog]:

Research Areas >> Cardiovascular Disease

Signaling Pathways >> Others >> Others

[References]

[1]. Jillian G Baker, et al. The selectivity of beta-adrenoceptor antagonists at the human beta1, beta2 and beta3 adrenoceptors. Br J Pharmacol. 2005 Feb;144(3):317-22.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₈H₃₁NO₄

[ Molecular Weight ]:
325.44300

[ Exact Mass ]:
325.22500

[ PSA ]:
59.95000

[ LogP ]:
2.75680

Safety Information

[ HS Code ]:
2922509090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2922509090

[ Summary ]:
2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%