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SALANNIN(P)

Names

[ CAS No. ]:
992-20-1

[ Name ]:
SALANNIN(P)

[Synonym ]:
SALANNIN(P)
Salannin

Biological Activity

[Description]:

Salannin, a limonoid bitter principle of the seed oil of Azadirachta indica, shows antiulcer and spermicidal activities. Salannin displays antibacterial activity towards both Gram-positive and Gram-negative bacteria[1][2].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Anti-infection >> Bacterial

[In Vivo]

Salannin (10, 20, 50 mg/kg; p.o.) shows a significant protective activity on Aspirin (HY-14654) induced gastric lesions[2]. Animal Model: Wistar rats, weighing 200-220 g (acetyl salicylic acid induced gastric lesions)[2] Dosage: 10, 20 and 50 mg/kg Administration: P.o. Result: Significantly and dose dependently inhibited acetyl salicylic acid-induced gastric lesions.

[References]

[1]. Divakar C. Madhu, et al. NTIULCER. ANTIBACTERIAL AND SPERMICIDAL ACTIVITIES OF SALANNIN.

[2]. Mohammad Asif, et al. A Review on Spermicidal Activities of Azadirachta indica. Journal of Pharmacognosy and Phytochemistry.

Chemical & Physical Properties

[ Molecular Formula ]:
C34H44O9

[ Molecular Weight ]:
596.70800

[ Exact Mass ]:
596.29900

[ PSA ]:
110.50000

[ LogP ]:
5.29100

Precursor & DownStream

Precursor

DownStream


Related Compounds