Scholaricine
Names
[ CAS No. ]:
99694-90-3
[ Name ]:
Scholaricine
[Synonym ]:
Curan-17-oic acid, 2,16-didehydro-12,19-dihydroxy-, methyl ester, (19S)-
Methyl (19S)-12,19-dihydroxy-2,16-didehydrocuran-17-oate
Biological Activity
[Description]:
Scholaricine (compound 13 ) is an alkaloid isolated from the leaf and stem-bark extracts of Alstonia spatulata. Scholaricine reverse multidrug resistance in vincristine-resistant KB cells with an IC50 value of 13.35 μM[1].
[Related Catalog]:
[References]
Chemical & Physical Properties
[ Density]:
1.4±0.1 g/cm3
[ Boiling Point ]:
519.5±50.0 °C at 760 mmHg
[ Molecular Formula ]:
C20H24N2O4
[ Molecular Weight ]:
356.42
[ Flash Point ]:
268.0±30.1 °C
[ Exact Mass ]:
356.173615
[ PSA ]:
82.03000
[ LogP ]:
1.41
[ Vapour Pressure ]:
0.0±1.4 mmHg at 25°C
[ Index of Refraction ]:
1.684
Safety Information
[ Hazard Codes ]:
Xi