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Naxagolide Hydrochloride

Names

[ CAS No. ]:
99705-65-4

[ Name ]:
Naxagolide Hydrochloride

[Synonym ]:
(-)-PHNO
Dopazinol Hydrochloride
(+)-Propyl-9-hydroxynaphthoxazine Hydrochloride
R(+)-PHNO
trans-N-n-propyl-9-hydroxy-2,3,4a,5,6,10b-hexahydro-4H-naphth[1,2b][1,4]oxazine
(+)-PHNO Hydrochloride
MK 458
Nazagolide HCl

Biological Activity

[Description]:

Naxagolide hydrochloride is an agonist of D2. Naxagolide hydrochloride can be used in study Parkinsonism[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Neurological Disease

[References]

[1]. Cutler NR, et al. Pharmacokinetics and dose proportionality of D2-agonist MK-458 (HPMC) in parkinsonism. Clin Pharmacokinet. 1992 Mar;22(3):223-30.  

Chemical & Physical Properties

[ Density]:
1.109g/cm3

[ Boiling Point ]:
391.7ºC at 760mmHg

[ Melting Point ]:
273-275ºC (dec.)

[ Molecular Formula ]:
C15H22ClNO2

[ Molecular Weight ]:
283.79400

[ Flash Point ]:
190.7ºC

[ Exact Mass ]:
283.13400

[ PSA ]:
32.70000

[ LogP ]:
3.23020

Related Compounds