COX-2-IN-18

Names

[ CAS No. ]:
1038061-96-9

[ Name ]:
COX-2-IN-18

Biological Activity

[Description]:

COX-2-IN-18 (Compound 3) is a potent inhibitor of COX-2. COX-2-IN-18 possesses good COX-2 inhibitory activity (IC50 = 0.775 μM) compared to the reference drug, Celecoxib (IC50 = 0.153 μM). COX-2-IN-18 has the potential for the research of cancer diseases[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Immunology/Inflammation >> COX

[References]

[1]. El-Azab AS, et al. Antitumor activity, multitarget mechanisms, and molecular docking studies of quinazoline derivatives based on a benzenesulfonamide scaffold: Cell cycle analysis. Bioorg Chem. 2020;104:104345.

Chemical & Physical Properties

[ Molecular Formula ]:
C18H19N3O3S2

[ Molecular Weight ]:
389.49

Related Compounds