LY135305

Names

[ CAS No. ]:
123199-75-7

[ Name ]:
LY135305

[Synonym ]:
3-naphthalen-1-yl-2-phenylpropan-1-amine hydrochloride

Biological Activity

[Description]:

LY 135305 is a thrombin activation inhibitor. LY 135305 inhibits spontaneous metastasis and increases animal survival[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease
Signaling Pathways >> Metabolic Enzyme/Protease >> Thrombin

[References]

[1]. R L Merriman, et al. Drug treatments for metastasis of the Lewis lung carcinoma: lack of correlation between inhibition of lung metastasis and survival. Cancer Res. 1989 Aug 15;49(16):4509-16.  

Chemical & Physical Properties

[ Boiling Point ]:
408.4ºC at 760 mmHg

[ Molecular Formula ]:
C19H20ClN

[ Molecular Weight ]:
297.82200

[ Flash Point ]:
195ºC

[ Exact Mass ]:
297.12800

[ PSA ]:
26.02000

[ LogP ]:
5.62710

[ Vapour Pressure ]:
7.01E-07mmHg at 25°C