L-366682

Names

[ CAS No. ]:
127819-96-9

[ Name ]:
L-366682

[Synonym ]:
L-366,682
cyclo(D-Trp-Ile-D-Pip-Pip-D-His-Pro)

Biological Activity

[Description]:

L-366682, a cyclic hexapeptide, possesses antagonism of oxytocin[1].

[Related Catalog]:

Research Areas >> Endocrinology
Signaling Pathways >> GPCR/G Protein >> Oxytocin Receptor

[References]

[1]. B V Clineschmidt, et al. Antagonism of oxytocin in rats and pregnant rhesus monkeys by the novel cyclic hexapeptides, L-366,682 and L-366,948. J Pharmacol Exp Ther. 1991 Mar;256(3):827-32.  

Chemical & Physical Properties

[ Molecular Formula ]:
C40H53N9O6

[ Molecular Weight ]:
755.90600

[ Exact Mass ]:
755.41200

[ PSA ]:
192.70000

[ LogP ]:
2.74360