2-(Pyridin-2-yl)acetic acid-d6 hydrochloride

Names

[ CAS No. ]:
1329799-67-8

[ Name ]:
2-(Pyridin-2-yl)acetic acid-d6 hydrochloride

Biological Activity

[Description]:

2-(Pyridin-2-yl)acetic acid-d6 (hydrochloride) is the deuterium labeled 2-(Pyridin-2-yl)acetic acid hydrochloride[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

Chemical & Physical Properties

[ Melting Point ]:
>108°C (dec.)

[ Molecular Formula ]:
C7H2ClD6NO2

[ Molecular Weight ]:
179.633890668

[ Appearance of Characters ]:
Solid | Light Beige to Light Brown to Dark Yellow

[ Storage condition ]:
Hygroscopic, -20°C Freezer, Under Inert Atmosphere

[ Stability ]:
Unstable in Solution, Hygroscopic

[ Water Solubility ]:
DMSO (Slightly), Methanol (Slightly), Pyridine (Slightly)

Related Compounds