Catharanthine Sulfate

Names

[ CAS No. ]:
153230-94-5

[ Name ]:
Catharanthine Sulfate

Biological Activity

[Description]:

Catharanthine Sulfate ((+)-3,4-Didehydrocoronaridine Sulfate) is an alkaloid isolated from Madagascar periwinkle, inhibits voltage-operated L-type Ca2+ channel, with anti-cancer and blood pressure-lowering activities[1].

[Related Catalog]:

Signaling Pathways >> Membrane Transporter/Ion Channel >> Calcium Channel
Research Areas >> Cancer
Research Areas >> Cardiovascular Disease

[References]

[1]. Jadhav A, et al. Catharanthine dilates small mesenteric arteries and decreases heart rate and cardiac contractility by inhibition of voltage-operated calcium channels on vascular smooth muscle cells and cardiomyocytes. J Pharmacol Exp Ther. 2013 Jun;345(3):383-92.

Chemical & Physical Properties

[ Molecular Formula ]:
C21H26N2O6S

[ Molecular Weight ]:
434.51

Related Compounds