HCV Peptide (35-44)

Names

[ CAS No. ]:
160214-01-7

[ Name ]:
HCV Peptide (35-44)

[Synonym ]:
C35-44
peptide C 35-44
YLLPRRGPRL
peptide C35-44

Biological Activity

[Description]:

HCV Peptide (35-44), a HCV core protein at positions 35 to 44, is a HLA-A2-restricted CTL epitope. HCV Peptide (35-44) inhibits NK cell activity via two distinct mechanisms, directly via KIR2DL2/3, and synergistically via the CD94:NKG2A receptor[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Inflammation/Immunology

[In Vitro]

HCV Peptide (35-44) (0-100 μM) 抑制总 NK 细胞群的脱颗粒。 HCV 肽 (35-44) 增加 HLA-C 和 HLA-E 的细胞表面表达[1]。

[References]

[1]. Cheent KS, et, al. P91 Dual mechanism of NK cell inhibition by the HCV core 35–44 peptide. BMJ journals. 60(Sup 2).

Chemical & Physical Properties

[ Molecular Formula ]:
C57H97N19O12

[ Molecular Weight ]:
1240.50000

[ Exact Mass ]:
1239.76000

[ PSA ]:
513.57000

[ LogP ]:
4.16690

Related Compounds