NH2-C2-amido-C2-Boc

Names

[ CAS No. ]:
1692613-62-9

[ Name ]:
NH2-C2-amido-C2-Boc

Biological Activity

[Description]:

NH2-C2-amido-C2-Boc is a PROTAC linker, which refers to the alkyl/ether composition. NH2-C5-NH-Boc can be used in the synthesis of a series of PROTACs, such as the PROTAC CDK2/9 Degrader-1 (HY-130709)[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> PROTAC >> PROTAC Linker

[Target]

Alkyl/ether


[References]

[1]. Zhou F, et al. Development of selective mono or dual PROTAC degrader probe of CDK isoforms. Eur J Med Chem. 2019 Dec 6;187:111952.

Chemical & Physical Properties

[ Molecular Formula ]:
C10H20N2O3

[ Molecular Weight ]:
216.28

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds