Abiraterone sulfate N-oxide

Names

[ CAS No. ]:
1993430-24-2

[ Name ]:
Abiraterone sulfate N-oxide

Biological Activity

[Description]:

Abiraterone sulfate N-oxide is a carboxylic acid. Abiraterone sulfate N-oxide also is a major metabolite of Abiraterone (HY-70013). Abiraterone sulfate N-oxide can be used for the research of prostate cancer[1][2].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others

[References]

[1]. Merel van Nuland, et al. Development and Validation of an LC-MS/MS Method for the Simultaneous Quantification of Abiraterone, Enzalutamide, and Their Major Metabolites in Human Plasma. Ther Drug Monit. 2017 Jun;39(3):243-251.  

[2]. Johan Monbaliu, et al. In Vitro and In Vivo Drug-Drug Interaction Studies to Assess the Effect of Abiraterone Acetate, Abiraterone, and Metabolites of Abiraterone on CYP2C8 Activity. Drug Metab Dispos. 2016 Oct;44(10):1682-91.  

Chemical & Physical Properties

[ Molecular Formula ]:
C24H31NO5S

[ Molecular Weight ]:
445.57

Related Compounds