MDH1-IN-1

Names

[ CAS No. ]:
2143463-31-2

[ Name ]:
MDH1-IN-1

Biological Activity

[Description]:

MDH1-IN-1 (Compound 5i) is a potent inhibitor of MDH1 with an IC50 of 6.79 μM. MDH1-IN-1 has the potential for the research of cancer diseases[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others

[References]

[1]. Naik R, et al. Methyl 3-(3-(4-(2,4,4-Trimethylpentan-2-yl)phenoxy)-propanamido)benzoate as a Novel and Dual Malate Dehydrogenase (MDH) 1/2 Inhibitor Targeting Cancer Metabolism. J Med Chem. 2017;60(20):8631-8646.

Chemical & Physical Properties

[ Molecular Formula ]:
C21H25NO4

[ Molecular Weight ]:
355.43


Related Compounds