5α-Cholesta-7,24-dien-3β-ol-d6

5α-Cholesta-7,24-dien-3β-ol-d6 is deuterium labeled 5α-Cholesta-7,24-dien-3β-ol. 5α-Cholesta-7,24-dien-3β-ol, a sterol, can be found in hamster cauda epididymal mature spermatozoa[1].

Research Areas >> Others

Signaling Pathways >> Others >> Others

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[2].

[1]. Awano M, et, al. Identification of cholesta-7,24-dien-3 beta-ol and desmosterol in hamster cauda epididymal spermatozoa. Lipids. 1989 Jul;24(7):662-4.

[2]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223.