Pomalidomide-PEG6-NH2 hydrochloride
Names
[ CAS No. ]:
2341841-01-6
[ Name ]:
Pomalidomide-PEG6-NH2 hydrochloride
Biological Activity
[Description]:
Pomalidomide-PEG6-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 6-unit PEG linker used in PROTAC technology.
[Related Catalog]:
[Target]
Cereblon
[In Vitro]
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Chemical & Physical Properties
[ Molecular Formula ]:
C25H36ClN3O10
[ Molecular Weight ]:
574.02
Safety Information
[ Hazard Codes ]:
Xi