COX-2/5-LOX-IN-1
Names
[ CAS No. ]:
2410384-50-6
[ Name ]:
COX-2/5-LOX-IN-1
Biological Activity
[Description]:
COX-2/5-LOX-IN-1 (compound 3a) is a potent and dual inhibitor of COX-2/5-LOX. COX-2/5-LOX-IN-1 is a benzothiophen-2-yl pyrazole carboxylic acid derivative. COX-2/5-LOX-IN-1 shows the most potent analgesic and anti-inflammatory activities surpassing that of Celecoxib and Indomethacin. COX-2/5-LOX-IN-1 shows potent COX-1, COX-2 and 5-LOX inhibitory activity with IC50s of 12.13, 0.4 and 4.96 μM, respectively[1].
[Related Catalog]:
[References]
Chemical & Physical Properties
[ Molecular Formula ]:
C14H10ClN3O4S2
[ Molecular Weight ]:
383.83