COX-2/5-LOX-IN-2
Names
[ CAS No. ]:
2410384-59-5
[ Name ]:
COX-2/5-LOX-IN-2
Biological Activity
[Description]:
COX-2/5-LOX-IN-2 (5b) is a potent and dual inhibitor of COX-2/5-LOX. COX-2/5-LOX-IN-2 is a benzothiophen-2-yl pyrazole carboxylic acid derivative. COX-2/5-LOX-IN-2 shows the most potent analgesic and anti-inflammatory activities surpassing that of Celecoxib and Indomethacin. COX-2/5-LOX-IN-2 shows potent COX-1, COX-2 and 5-LOX inhibitory activity with IC50s of 5.40, 0.01 and 1.78 μM, respectively[1].
[Related Catalog]:
[References]
Chemical & Physical Properties
[ Molecular Formula ]:
C18H13N3O4S2
[ Molecular Weight ]:
399.44