KRAS inhibitor-20
Names
[ CAS No. ]:
2411786-32-6
[ Name ]:
KRAS inhibitor-20
Biological Activity
[Description]:
KRAS inhibitor-20 is a small molecular inhibitor of KRasG12C, the oncogenic mutant. KRAS inhibitor-20 inhibits KRasG12C with the IC50 value <10 nM[1].
[Related Catalog]:
[Target]
KRAS(G12C):<10 nM (IC50, [1])
[In Vitro]
KRAS inhibitor-20 (compound 12b) results KRasG12C alkylation human lung cancer adenocarcinoma (HCC 1171) with an EC50 value of 3.3 nM[1].
[References]
Chemical & Physical Properties
[ Molecular Formula ]:
C31H40F4N6O2
[ Molecular Weight ]:
604.68