Antitubercular agent-20

Names

[ CAS No. ]:
2413124-92-0

[ Name ]:
Antitubercular agent-20

Biological Activity

[Description]:

Antitubercular agent-20 (Compound 2d) is an orally active antitubercular agent. Antitubercular agent-20 shows excellent activity against MTB H37Rv and MDR-MTB strains (MIC: ＜0.016 µg/ml). Antitubercular agent-20 has low cytotoxicity and good tolerance in BALB/c mice[1].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Anti-infection >> Bacterial

[References]

[1]. Wang A, et al. Identification of benzothiazinones containing 2-benzyl-2,7-diazaspiro[3.5]nonane moieties as new antitubercular agents. Eur J Med Chem. 2020 Aug 15;200:112409.

Chemical & Physical Properties

[ Molecular Formula ]:
C25H22F6N4O3S

[ Molecular Weight ]:
572.52

Related Compounds