Anticancer agent 62

Names

[ CAS No. ]:
2413148-58-8

[ Name ]:
Anticancer agent 62

Biological Activity

[Description]:

Anticancer agent 62 (compound 4c) is a potent anticancer agent. Anticancer agent 62 shows antiproliferative activity in HepG2, Bel-7402 and MCF-7 cancer cells, with IC50 values of 0.019, 0.060 and 0.016 μM, respectively. Anticancer agent 62 shows effective tumor growth inhibition[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others

[In Vivo]

Anticancer agent 62 (compound 4c) (BALB/c mice, 0-50 mg/kg, IP, once) inhibits human HepG2 xenograft mouse tumor growth by 71.7% at 25 mg/kg[1].

[References]

[1]. Liu Y, et al. Synthesis and structure-activity relationship study of water-soluble carbazole sulfonamide derivatives as new anticancer agents. Eur J Med Chem. 2020 Apr 1;191:112181.

Chemical & Physical Properties

[ Molecular Formula ]:
C20H18N3Na2O8PS

[ Molecular Weight ]:
537.39

Related Compounds