HIV-1 inhibitor-39

Names

[ CAS No. ]:
2414099-82-2

[ Name ]:
HIV-1 inhibitor-39

Biological Activity

[Description]:

HIV-1 inhibitor-39 (compound 3c) is a potent HIV-1 inhibitor with an EC50 of >112.88 µM. HIV-1 inhibitor-39 shows anti-RT (HIV-1 reverse transcriptase) activities with an IC50 of 15.75 µM. HIV-1 inhibitor-39 shows cytotoxicity for MT-4 cells with an CC50 of 112.9 µM[1].

[Related Catalog]:

Signaling Pathways >> Anti-infection >> HIV
Research Areas >> Infection

[Target]

HIV-1:>112.88 μM (EC50)


[References]

[1]. Buemi MR, et al. Inhibition of HIV-1 RT activity by a new series of 3-(1,3,4-thiadiazol-2-yl)thiazolidin-4-one derivatives. Bioorg Med Chem. 2020 Apr 15;28(8):115431.

Chemical & Physical Properties

[ Molecular Formula ]:
C20H17ClN4O4S4

[ Molecular Weight ]:
541.09

Related Compounds